New release: Six2 and CTCF ChIP-seq datasets of wildtype mouse embryonic facial tissues (E10.5 - E13.5)
Published 16 April 2026
New ChIP-seq datasets are now available in FaceBase, profiling Six2 transcription factor binding and CTCF-defined topologically associating domains in wildtype mouse embryonic facial tissues at stages E10.5 through E13.5. Input libraries are included as controls. Together these data support investigation of gene regulatory networks and chromatin architecture during craniofacial morphogenesis.
Contributors: Jingyue Xu, Han Liu and Rulang Jiang (Cincinnati Children’s Hospital, Medical Center)
Description:
We performed a ChIP-seq assay using a Six2 antibody to identify endogenous Six2-binding genomic loci in mouse embryonic facial tissues. We performed a ChIPseq assay using the CTCF antibody to identify topologically associating domains and boundaries. We generated ChIP libraries and sent them for next-generation sequencing. We also generated input libraries as control samples.
FaceBase Dataset:
Jingyue Xu, Han Liu, Rulang Jiang. Six2 and CTCF ChIP-seq datasets of wildtype mouse embryonic facial tissues (E10.5 - E13.5). FaceBase Consortium https://doi.org/10.25550/7Z-41CW (2026).