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The public portion of the FaceBase Annual Meeting will be held on May 1st at the Harvard New Research Building in Boston.
Click here for details and to register to attend.

Ontology of Craniofacial Development and Malformation (OCDM)

To satisfy the need for standardized terminologies and intelligent data integration, we are developing the Ontology of Craniofacial Development and Malformation. When complete, this ontology will describe several realms of anatomy and development relevant to FaceBase, including:

  • Human craniofacial anatomy and development
  • Mouse craniofacial anatomy and development
  • Zebrafish craniofacial anatomy and developmemnt
  • Craniofacial malformations in human, mouse and zebrafish
  • Mappings between human, mouse and zebrafish anatomy

The OCDM is written in OWL 2, and consists of an umbrella ontology, which imports a set of sub-ontologies. Currently these ontologies are:

Category Name Description
OCDM Ontology of Craniofacial Development and Malformation Umbrella ontology that imports all of the other sub-ontologies
CHO Craniofacial Human Ontology Normal human craniofacial anatomy, both adult and developmental, derived from our Foundational Model of Anatomy (FMA)
CMO Craniofacial Mouse Ontology Normal mouse craniofacial anatomy, both adult and developmental
CZO Craniofacial Zebrafish Ontology Normal zebrafish craniofacial anatomy, both adult and developmental
CHMO Craniofacial Human Malformation Ontology Abnormal human craniofacial anatomy and phenotypes
CMMO Craniofacial Mouse Malformation Ontology Abnormal mouse craniofacial anatomy and phenotypes
CHMMO Craniofacial Human-Mouse Mappings Ontology Mappings of classes in the CHO to related (homologous) structures in the CMO
CHM3O Craniofacial Human-Mouse Malformation Mappings Ontology Mappings of classes in the CHMO to related (homologous) structures in the CMMO
AEO Attribute Entity Ontology Ontology which contains measurements and other descriptors
CET Craniofacial External Terminology Mappings from external ontologies that don't easily fit into the OCDM

All ontologies are in Protege OWL format, and can be loaded into the latest version of Protege. Ontologies refer to other ontologies via the OWL import mechanism.

For further information and to download the latest version see the project webpage.