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Gene Wiki | FaceBase

Access the webcasts and slides from the FaceBase Bootcamp! Click here for links to the materials

Gene Wiki

The Gene Wiki was initiated during the first phase of FaceBase and contains information on a number of genes known to play a role in craniofacial development, specifically for cleft lip and palate as this phase was focused on midface development. There are Wikipedia pages available for many of these genes thanks for editors from FaceBase 1.

Original description

The FaceBase project will build on Gene Wiki to create a craniofacial- specific presence for genes that play a role in cleft lip and palate. To pilot the use of the Gene Wiki, we’ve taken a small number of genes known to play a role in craniofacial development and begun editing them using volunteer editors from the craniofacial community. The Gene Wiki will also link to related concepts like diseases, physiological structures, and cell types to provide detailed context to the genetic data.

The people listed below agreed to write some initial entries for GeneWiki, but contributions aren’t restricted to them. If you are interested in adding to the entry for one of these genes, please do! If you’d like to suggest a gene to be added to the list, please contact Jeff Murray, University of Iowa.

Gene Editor
8Q24 Aline L Petrin, University of Iowa
ARHGAP29  
AXIN2 Renato Menezes, University of Pittsburgh
BMP4 Satoshi Suzuki, Aichi-Gakuin University
Cleft lip and palate Kate Durda, University of Iowa
FGFR1 Jeff Murray, University of Iowa
FGFR2 Beth Erickson, University of Iowa
FOXE1 M. Adela Mansilla, University of Iowa
IRF6 Jeff Murray, University of Iowa
locus 8q24  
MAFB M. Adela Mansilla, University of Iowa
MMP3 Ariadne Letra, University of Pittsburgh
MSX1 Peter Jezewski, Forsyth Institute, Harvard School of Dental Medicine
MSX2 (Msh homeobox 2) Peter Jezewski, Forsyth Institute, Harvard School of Dental Medicine
MSX3 Peter Jezewski, Forsyth Institute, Harvard School of Dental Medicine
NOG  
NTN1  
P63 Michael James Dixon, University of Manchester
PAX7 Azeez Butali, University of Iowa
PDGFC Mary L. Marazita, University of PIttsburgh
PTCH M. Adela Mansilla, University of Iowa
SATB2 David FitzPatrick, Medical Research Council, Edinburgh
SOX9 David FitzPatrick, Medical Research Council, Edinburgh
SUMO1 (Small ubiquitin-related modifier 1) Astanand Jugessur, Norwegian Institute of Public Health
TBX22 Rulang Jiang, University of Rochester Medical Center
TCOF (Treacle protein) Michael James Dixon, University of Manchester
TFAP2A If you are interested in working on the entry for this gene, please let us know! Contact Jeff Murray, University of Iowa - ask if this is okay
TP63  
VAX1 Azeez Butali, University of Iowa
WNTS Andrew Lidral, University of Iowa