News & Events

FaceBase Hub publication in JDR Special Issue (02 August 2022)

The Hub is pleased to announce a new paper that was just published in a special issue of the Journal of Dental Research (Data-Driven Analytics for Dental, Oral, and Craniofacial Health Care) titled “FaceBase: A Community-Driven Hub for Data-Intensive Research”. This review article summarizes the last two and a half years of FaceBase’s community-driven, self-curation model and describes the resulting varied datasets published as a result. It also describes the importance of FAIR principles for data sharing.

Schuler RE, Bugacov A, Hacia JG, et al. FaceBase: A Community-Driven Hub for Data-Intensive Research. Journal of Dental Research. August 2022. doi:10.1177/00220345221107905

Abstract:

The FaceBase Consortium, funded by the National Institute of Dental and Craniofacial Research of the National Institutes of Health, was established in 2009 with the recognition that dental and craniofacial research are increasingly data-intensive disciplines. Data sharing is critical for the validation and reproducibility of results as well as to enable reuse of data. In service of these goals, data ought to be FAIR: Findable, Accessible, Interoperable, and Reusable. The FaceBase data repository and educational resources exemplify the FAIR principles and support a broad user community including researchers in craniofacial development, molecular genetics, and genomics. FaceBase demonstrates that a model in which researchers “self-curate” their data can be successful and scalable. We present the results of the first 2.5 y of FaceBase’s operations as an open community and summarize the data sets published during this period. We then describe a research highlight from work on the identification of regulatory networks and noncoding RNAs involved in cleft lip with/without cleft palate that both used and in turn contributed new findings to publicly available FaceBase resources. Collectively, FaceBase serves as a dynamic and continuously evolving resource to facilitate data-intensive research, enhance data reproducibility, and perform deep phenotyping across multiple species in dental and craniofacial research.

You can view all FaceBase publications here.

Winners of the 2022 FaceBase Poster Competition! (21 June 2022)

We had an amazing time at the 2022 FaceBase Community Forum last week with great talks and interactions. Needless to say, it was also a joy to be able to see colleagues in person for the first time in years! We’ll be posting some materials available for the public soon.

But first, we wanted to celebrate our poster finalists! The posters with the top scores were:

First Place (Tie)

• Ching-Fang Chang (Cincinnati Children’s Hospital), “Alleviation of Ciliopathic Craniofacial Anomalies by Disrupting Sufu-Gli Interaction”
• Junjun Jing (USC), “Spatiotemporal Single-cell Atlas Reveals Cell Lineage Diversification During Tooth Morphogenesis”
• Tiange Qu (UCSF), “Deconstructing Calcineurin/NFAT Signaling in Species with Distinct Midfacial Outgrowth “

Second Place (Tie)

• Brandon Chacon (UCSF), “Midface Epithelium scRNAseq Reveals Spatiotemporal Dynamics in Cleft Lip/Palate Model”
• Viviana Hermosilla Aguayo (UCSF), “Tissue-specific Roles of ESCRT Machinery Component VPS25 in Craniofacial Morphogenesis”

Third Place (Tie)

• Azeez Alade (Iowa Institute for Oral Health Research), “Shared Genetic Risk Between Cleft Subtypes in the African Population”
• Jifan Feng (USC), “TGF-β Signaling Regulates Pharyngeal Muscle Development via Mediating Cell-cell Interaction”
• Mingyi Zhang (USC), “Arid1b is Indispensable in Regulating Mesenchymal Stem Cell Homeostasis”

Congratulations to our winners and all of the poster presenters at this year’s Community Forum!

Registration is open for the FaceBase Community Forum on Tuesday, June 14th! (22 April 2022)

Registration is now open for the 2022 FaceBase Community Forum!

Join the craniofacial research community for a day of in-person and virtual knowledge sharing at the 2nd Annual FaceBase Community Forum!

This year, we’ll be holding the Forum in-person at the Bolger Center in Bethesda, Maryland on Tuesday, June 14th. There will be invited talks, a forum panel, poster competition and special trainee programming!

You still have the option to join remotely via Zoom for the main meeting. However, in-person attendees will have access to special demos and workshops before the main meeting and showing their posters in the poster hall.

Check out the event page for more complete information!

Save the date for the 2nd Annual FaceBase Community Forum on Tuesday, June 14th! (13 April 2022)

Join the craniofacial research community for a day of in-person and virtual knowledge sharing at the 2nd Annual FaceBase Community Forum!

This year, we’ll be holding the Forum in-person at the Bolger Center in Bethesda, Maryland on Tuesday, June 14th. There will be invited talks, a forum panel, poster competition and special trainee programming!

You still have the option to join remotely via Zoom for the main meeting. However, in-person attendees will have access to special demos and workshops before the main meeting and showing their posters in the poster hall.

Registration will open next week and will include more information on fees and logistics for in-person attendance.

Check this event page, your inbox (if you’re a subscriber or member), and our Twitter account next week for the links!

Upcoming FaceBase Bootcamp for Users & Data Contributors on April 27th (24 March 2022)

The FaceBase Hub is hosting another bootcamp which includes sessions for both users of FaceBase and those who wish to contribute data. We will also be introducing new features such as imaging data search, an updated imaging data pipeline and annotations capability.

Date and Times

Wednesday, April 27, 2022
12:00 pm to 4:30 pm EDT / 9:00 am to 1:30 pm PDT

Format

The bootcamp has two scheduled tracks - one focused for users and one for data contributors:

• 12:00 pm to 1:30 pm Eastern - Users track - The FaceBase Hub will walk through the resources available on FaceBase, best practices for using the search interface, proper citation practices and how to export data.
• 2:00 pm to 4:30 pm Eastern - Data Contributors track - Learn about contributing data and how data is curated along with a live demonstration of adding metadata and uploading data.

Zoom

Zoom details will be emailed to registrants and replay videos will be available after the event.

Details

Just click this link for details and how to register: https://www.facebase.org/training/2022-04-27/

If you have any questions, please send them to help@facebase.org.